Klaudia Talohole Angula
Windhoek,Namibia
Summary
I am a dedicated chemist with knowledge of lab compliance requirements and safety protocols. I am fully capable of keeping laboratory equipment and instruments in optimal condition, as well as ordering supplies, completing inventories and maintaining records. An energetic employee well-versed in leading group discussions and managing projects. Thus a diligent chemistry professional conducting innovative research within the pharmaceutical drug development industry while transferring knowledge in academia.
Work History
Senior Laboratory Technologist
University of Namibia
Windhoek, Namibia
08.2019 - Current
Overall laboratory management (procurement of resources, HSE), develop and review practical manuals, , technical and academic teaching support, research, ad hoc
Laboratory Technologist
University of Namibia
Windhoek, Namibia
09.2013 - 07.2019
Laboratory (management, HSE and procurement, technical support and research.
Laboratory Shift-Chemist
University of Namibia
Arandis, Erongo
03.2010 - 08.2013
- Health Safety & Environment, sampling, analytical techniques (XRF, ICP, auto titration, GC), QC/QA systems and reporting (LIMS), Inventories, procurement. Ensure compliance with ISO 17025 and other laboratory regulatory standards.
Process Technician
Rio-Tinto's Rossing Uranium
Arandis, Erongo
06.2007 - 10.2008
- Monitoring process plant operational control parameters, KPI's and sampling point conditioning and sampling, inventories
Lab Technician
University of Namibia
Windhoek, Khomas
09.2006 - 05.2007
- Set-up laboratory experiments (prepared buffers and reagents), marking laboratory reports and perform chemical inventories, Maintain HSE compliance.
Physical Science Teacher
Ministry of Education
Uis, Erongo
02.2006 - 08.2006
- Class registered teacher and school's science teacher grade 8 to 10. Lesson preparations, all teaching administration requirements.
Education
PhD - Pharmaceutical Chemistry
01.2020 - 11.2022
Novel drug development, organic synthesis, analytical techniques (HPLC, NMR), infectious diseases, biological data analysis and interpretation and structure activity relationships, HSE, publishing and conference presentation and assist with research co-supervision of the MSc students.
Publications:
1. Phelelisiwe S. Dube, Klaudia T. Angula, Lesetja J. Legoabe, Audrey Jordaan, Jan M.B. Zarella, Digby F. Warner, Stone J. Doggett, and Richard M. Beteck. Quinolone-3-amidoalkanol: A New Class of Potent and Broad-Spectrum Antimicrobial Agent. ACS Omega (2023), 8, 17086−17102.
2. K.T. Angula; L J. Legoabe; A. Jordaan; DF. Warner. Investigation of quinolone-tethered aminoguanidine as novel antibacterial agents, Archive der Pharmazie (2022), http://doi.org/10.1002/ardp.202200172
3. Angula, K.T.; Legoabe, L.J.; Beteck, R.M. Chemical Classes Presenting Novel Antituberculosis Agents Currently in Different Phases of Drug Development: A 2010–2020 Review, Pharmaceuticals(2021), 14, 461. https://doi.org/10.3390/ph14050461
4. K.T. Angula, L.J. Legoabe, T. Swart, H.C. Hoppe, R.M. Beteck, Synthesis and in vitro antitrypanosomal evaluation of novel 6-heteroarylidene-substituted quinolone derivatives, European Journal of Medicinal Chemistry (2021), doi: https://doi.org/10.1016/j.ejmech.2021.113913.
MSc - Pharmaceutical Chemistry
02.2015 - 12.2016
Novel drug development, organic synthesis, analytical techniques (HPLC, NMR), infectious diseases, biological data analysis and interpretation and structure activity relationships, HSE, publishing and conference presentation.
Publications:
1. Klaudia T. Amakali,1Lesetja J. Legoabe,1,* Anél Petzer,1,2. Synthesis and evaluation 2-benylidene-1-tetralone derivatives for monoamine oxidase inhibitory activity. Central Nervous System Agents in Medicinal Chemistry (2018), 18: 1-10 https://doi.org/10.1055/a-0620-8309
1. Klaudia T. Amakali,a Lesetja J. Legoabe,a,* Anél Petzer,a,b and Jacobus P. Petzer a,b. Synthesis and in vitro evaluation of 2-heteroarylidene-1-tetralone derivatives as monoamine oxidase inhibitors. Drug Research (2018), 18: 1-14
BSc (Hons) - Chemistry
02.2009 - 03.2010
Academic honours in Chemistry.
Publication:
Burger, B.V*, leRoux M., Marx, B., Herbert, S.A. Amakali, K.T. Development of second-generation sample enrichment probe for improved sorptive analysis of volatile organic compounds. Journal of chromatography A (2011), 1218: 1567-1575.
BSc - Chemistry and Physiological & molecular biology
02.2002 - 12.2005
Skills
- Laboratory Information Management System (LIMS) proficiency,
- ISO [17025] quality standards
- SOP adherence
- (SAP, ITS)
- Communication skills
- Equipment procurement
- Microsoft Office
- Research plan
- Laboratory stock control
- Laboratory safety protocol
- Sample preparation
Languages
Oshiwambo
NATIVE LANGUAGE
English
Advanced
A1
Timeline
North-West University - PhD, Pharmaceutical Chemistry
01.2020 - 11.2022
Senior Laboratory Technologist - University of Namibia
08.2019 - Current
North-West University - MSc, Pharmaceutical Chemistry
02.2015 - 12.2016
Laboratory Technologist - University of Namibia
09.2013 - 07.2019
Laboratory Shift-Chemist - University of Namibia
03.2010 - 08.2013
University of Stellenbosch - BSc (Hons), Chemistry
02.2009 - 03.2010
Process Technician - Rio-Tinto's Rossing Uranium
06.2007 - 10.2008
Lab Technician - University of Namibia
09.2006 - 05.2007
Physical Science Teacher - Ministry of Education
02.2006 - 08.2006
University of Namibia - BSc, Chemistry and Physiological & molecular biology
02.2002 - 12.2005
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