Klaudia Talohole Angula
Windhoek,Namibia
Summary
I am a dedicated chemist with knowledge of lab compliance requirements and safety protocols. I am fully capable of keeping laboratory equipment and instruments in optimal condition, as well as ordering supplies, completing inventories and maintaining records. An energetic employee well-versed in leading group discussions and managing projects. Thus a diligent chemistry professional conducting innovative research within the pharmaceutical drug development industry while transferring knowledge in academia.
Work history
Senior Laboratory Technologist
University of Namibia
Windhoek, Namibia
2019.08 - Current
Overall laboratory management (procurement of resources, HSE), develop and review practical manuals, , technical and academic teaching support, research, ad hoc
Laboratory Technologist
University of Namibia
Windhoek, Namibia
2013.09 - 2019.07
Laboratory (management, HSE and procurement, technical support and research.
Laboratory Shift-Chemist
University of Namibia
Arandis, Erongo
2010.03 - 2013.08
- Health Safety & Environment, sampling, analytical techniques (XRF, ICP, auto titration, GC), QC/QA systems and reporting (LIMS), Inventories, procurement. Ensure compliance with ISO 17025 and other laboratory regulatory standards.
Process Technician
Rio-Tinto's Rossing Uranium
Arandis, Erongo
2007.06 - 2008.10
- Monitoring process plant operational control parameters, KPI's and sampling point conditioning and sampling, inventories
Lab Technician
University of Namibia
Windhoek, Khomas
2006.09 - 2007.05
- Set-up laboratory experiments (prepared buffers and reagents), marking laboratory reports and perform chemical inventories, Maintain HSE compliance.
Physical Science Teacher
Ministry of Education
Uis, Erongo
2006.02 - 2006.08
- Class registered teacher and school's science teacher grade 8 to 10. Lesson preparations, all teaching administration requirements.
Education
PhD - Pharmaceutical Chemistry
2020.01 - 2022.11
Novel drug development, organic synthesis, analytical techniques (HPLC, NMR), infectious diseases, biological data analysis and interpretation and structure activity relationships, HSE, publishing and conference presentation and assist with research co-supervision of the MSc students.
Publications:
1. Phelelisiwe S. Dube, Klaudia T. Angula, Lesetja J. Legoabe, Audrey Jordaan, Jan M.B. Zarella, Digby F. Warner, Stone J. Doggett, and Richard M. Beteck. Quinolone-3-amidoalkanol: A New Class of Potent and Broad-Spectrum Antimicrobial Agent. ACS Omega (2023), 8, 17086−17102.
2. K.T. Angula; L J. Legoabe; A. Jordaan; DF. Warner. Investigation of quinolone-tethered aminoguanidine as novel antibacterial agents, Archive der Pharmazie (2022), http://doi.org/10.1002/ardp.202200172
3. Angula, K.T.; Legoabe, L.J.; Beteck, R.M. Chemical Classes Presenting Novel Antituberculosis Agents Currently in Different Phases of Drug Development: A 2010–2020 Review, Pharmaceuticals(2021), 14, 461. https://doi.org/10.3390/ph14050461
4. K.T. Angula, L.J. Legoabe, T. Swart, H.C. Hoppe, R.M. Beteck, Synthesis and in vitro antitrypanosomal evaluation of novel 6-heteroarylidene-substituted quinolone derivatives, European Journal of Medicinal Chemistry (2021), doi: https://doi.org/10.1016/j.ejmech.2021.113913.
MSc - Pharmaceutical Chemistry
2015.02 - 2016.12
Novel drug development, organic synthesis, analytical techniques (HPLC, NMR), infectious diseases, biological data analysis and interpretation and structure activity relationships, HSE, publishing and conference presentation.
Publications:
1. Klaudia T. Amakali,1Lesetja J. Legoabe,1,* Anél Petzer,1,2. Synthesis and evaluation 2-benylidene-1-tetralone derivatives for monoamine oxidase inhibitory activity. Central Nervous System Agents in Medicinal Chemistry (2018), 18: 1-10 https://doi.org/10.1055/a-0620-8309
1. Klaudia T. Amakali,a Lesetja J. Legoabe,a,* Anél Petzer,a,b and Jacobus P. Petzer a,b. Synthesis and in vitro evaluation of 2-heteroarylidene-1-tetralone derivatives as monoamine oxidase inhibitors. Drug Research (2018), 18: 1-14
BSc (Hons) - Chemistry
2009.02 - 2010.03
Academic honours in Chemistry.
Publication:
Burger, B.V*, leRoux M., Marx, B., Herbert, S.A. Amakali, K.T. Development of second-generation sample enrichment probe for improved sorptive analysis of volatile organic compounds. Journal of chromatography A (2011), 1218: 1567-1575.
BSc - Chemistry and Physiological & molecular biology
2002.02 - 2005.12
Skills
- Laboratory Information Management System (LIMS) proficiency,
- ISO [17025] quality standards
- SOP adherence
- (SAP, ITS)
- Communication skills
- Equipment procurement
- Microsoft Office
- Research plan
- Laboratory stock control
- Laboratory safety protocol
- Sample preparation
Languages
Oshiwambo
NATIVE LANGUAGE
English
Advanced
A1
Timeline
North-West University - PhD, Pharmaceutical Chemistry
2020.01 - 2022.11
Senior Laboratory Technologist - University of Namibia
2019.08 - Current
North-West University - MSc, Pharmaceutical Chemistry
2015.02 - 2016.12
Laboratory Technologist - University of Namibia
2013.09 - 2019.07
Laboratory Shift-Chemist - University of Namibia
2010.03 - 2013.08
University of Stellenbosch - BSc (Hons), Chemistry
2009.02 - 2010.03
Process Technician - Rio-Tinto's Rossing Uranium
2007.06 - 2008.10
Lab Technician - University of Namibia
2006.09 - 2007.05
Physical Science Teacher - Ministry of Education
2006.02 - 2006.08
University of Namibia - BSc, Chemistry and Physiological & molecular biology
2002.02 - 2005.12